Redox Modifications and Hematological Neoplasms-an Overview

Article history Received: 05-02-2014 Revised: 06-08-2014 Accepted: 05-01-2015 Abstract: Due to our current interest in the study of the relationship between hematological malignancies and oxidative stress, in this review we addressed the recent finding regarding this issue, focusing on the clinical findings concerning the oxidative status of patients diagnosed with hematological cancers. This study is a descriptive review of the literature. For the theoretical scientific background, we used the electronic PubMed search engines. It is possible to find several studies involving oxidative stress and hematological cancer, analyzing the many ways regarding the imbalance of excessive free radical production and its neutralization by antioxidants. The present review highlights the need for studies to understand the main role of oxidative stress as a cause or consequence of hematological neoplasms, as well as its participation as beneficial for either the host or tumor cells.